CER Groupe

IN VITRO/VIVO PLATFORM

• 12500+ sqm of animal facilities covering SPF/SOPF, BSL-2 and BSL-3 areas
• Small to large animal species, in vivo imaging systems + in vitro imaging platform
• From discovery and pharmacology to GLP toxicology preclinical models
• Integrated solution : model dvlpmt, item preparation, analytical phases, ..
• Biologics, vaccines, ATMPs, immunotherapies, infectiology, oncology and medical devices

BIOPRODUCTION PLATFORM

• Hapten synthesis and conjugation : small molecules, hormones, …
• ISO9001-certified biologic design, development and production : antibodies (mAb, rAb, pAb, VHH, recAb), proteins (native, variants) and viral vectors (lentivirus, AAV)
• Bacterial and mammalian USP platforms up to 10 liter stirred-tank bioreactor ; complete DSP platform (FPLC, TFF, lyo)
• Biologic characterization : physico-chemical, structural and biological characteristics
• Product development and manufacturing : applications, site-selective conjugation technologies, product formulation, freeze-drying
• Bioprocess modeling and digitalization

ANALYTICAL PLATFORM

• Mass spectrometry : targeted/untargeted analysis including metabolomics, proteomics, glycan profiling
• Flow cytometry : 13-color analyzer (x2) and sterile cell sorter ; humoral and cellular response, population phenotyping, functional assay
• Gene expression : automated RNA/DNA extraction, qPCR thermocycler
• Biomarker analysis : single or multiplex colorimetry, fluorescence, luminescence (incl. MSD technology)
• Cell-based assay : in vitro cell imaging (proliferation, toxicity, internalization, phagocytosis, oxydative stress, inflammatory response)
• Molecular interaction analysis : biolayer interferometry (BLI, Octet) system for affinity, quantitation, match pairing, …

FOOD/FEED PLATFORM

• ISO17025-certified routine analysis through a flexible scope with >12000 matrix/compounds combinations
• Physico-chemical (LC, GC, HPLC, MS, HRMS, …) and binding (ELISA, FCIA, …) technologies
• National Reference Laboratory for allergens, veterinary drug residues, plant/marine/myco toxins

Bioproduction

Our bioproduction activities constitute a comprehensive range of pre-GMP services, from biological design and development to pre-clinical production. These are supported by state-of-the-art analytical platforms for biological characterization.

Custom recombinant proteins

Our integrated solutions for recombinant protein production are characterized by a high success rate, even for challenging proteins.

Custom antibodies

CER Groupe has developed expertise in (monoclonal and polyclonal) antobody production over more than 25 years. Custom viral vectors Viral vectors are recombinant viruses that are used to deliver genetic material into target cells and are used or research, biomanufacturing and therapeutic applications.

USP/DSP development and modeling

Optimizing a bioprocess greatly impacts several parameters such as target biological productivity, the quality profile of a product or production coasts.

Biologic testing and characterization

Biological characterization is critical for understanding the quality of the product and potential sources of variation in their activity

Non-clinical services

Our expertise in non-clinical services is recognized by biotech and pharmaceutical companies, in particular within the immunology, oncology, infectiology and implantable medical devices sectors.

Discovery services

CER Groupe continuously develops new custom models, both in vitro or in various animal models.

Pharmacology

Pharmacology - the study of the biological effects of a compound in a living organism - gives you insight into how well your compound might be able to treat your targeted indication. Immuno-monitoring Our team of experts helps you to design appropriate immuno-monitoring investigation strategies, in order to accelerate the development of your drug and integrate it during your pre-clinical in-vitro and in-vivo studies.

GLP Residues Studies

We manage routine residues-testing studies thanks to our GLP certification, our facilities dedicated to production animals, and our highly specialized capabilities in mass spectrometry analysis.

GLP safety studies

Our safety study services are GLP certified and aligned with the best standards: ICH, VICH, and ISO. Batch testing and characterization At CER Groupe, we have the necessary equipment to characterize your biological products in terms of both physico-chemical and activity parameters.

Analytical support

Our team of scientific and technical experts strives to deliver reliable results, from feasibility studies to assay development and validation, and for routine testing

Food & feed testing

We provide flexible, high-quality support in both routine and custom analyses, from small molecules to proteomic analysis, in order to ensure food and feed safety.

Contaminant analysis - residues, allergens and toxins

CER Groupe has developed extensive expertise in food allergens analysis over decades.

Novel food

CER Groupe offers a competitive and comprehensive range of services for Novel Foods designation at the pre-clinical level.

Functional food

We use our expertise in bioproduction, agri-tech, food, and pre-clinical evaluations to support the research and development of your functional food innovations.

Food of animal origin control

CER Groupe has considerable experience in animal food control and process validated and certified methods that align with current regulations for established analysis.

Bioproduction, Non-clinical development, Preclinical development, food and feed testing, animal health, human health, diagnostics, ATMPs, medical devices, molecular engineering, infectiology, oncology, immunology, residue and contaminants detection, allergens, anitbodies, viral vectors.