Research Center Pharmaceutical Engineering GmbH

RCPE Pilot Plant (ISO 9001, ISO 14001)

The pilot plant is extensively equipped, including a continuous extrusion system with hot-melt extruders, a wet extruder, a die-face cutter, a pelletizer, various feeding systems, a fully-instrumented laboratory tablet press, fluid-bed systems, a compaction simulator, granulators, nano-spray driers, capsule filling systems, filters, blenders, drug printers, crystallizers, coaters and much more.
The machines are used for process development, process understanding and the implementation of process-analytical tools for in-process monitoring, control and process optimization.

Regular maintenance and certification of the equipment and extensive training of the employees guarantee top research results and performance.

• State-of-the-art pilot plant
• Mixers, wet & dry granulators, compaction, coating, spray drying, continuous processing, etc.
• Online NIR, Raman, UVVis, OCT, NIR GMP certified
• 500 m² of state-of-the-art facilities
• Pharma Standard Clean Rooms (ISO 7) up to OEB 4 level

RCPE Laboratory Facilities (ISO 9001, ISO 14001)

Over the last years, RCPE has developed its own process and analytical laboratory with state-of-the-art equipment.

At the laboratory facility solid dosage forms are investigated (powders, tablets, pills, pellets, granules, capsules, etc.) which are relevant to pharmaceutical applications. For material characterization, comprehensive laboratory equipment is available. The analytics laboratory (chemical identification via UPLC, HPLC, 2 online NIRs, FTIR, online-Raman, UV-Vis, dissolution, particle analysis, structure, flowability, DSC, X-ray, etc.) comprises state-of-the-art equipment as well.

• State-of-the-art analytical laboratory
• Detailed maintenance plans
• Equipment certification available

RCPE provides independent R&D in the field of pharmaceutical engineering, bridging the gap between science and industrial applications, ensuring pharmaceutical companies have the necessary predictive tools, methods and approaches to benefit from regulatory and industry-driven initiatives such as Quality by Design.

It is our intention to make our research capabilities and technological background available for companies on a service basis. Typical examples include measurements using our vast experimental and analytical capabilities, literature studies, feasibility studies, design studies, simulation work and other types of services.

Benefits

• Diverse Research Activities
  small preparatory studies up to extensive multi-year research programs are possible
• Proven Scientific Excellence
  multi-disciplinary teams, dedicated to customer needs
• Maximum Output for Partners
  defined & clear IPR strategies
• Flexible Business Models
  funded & non-funded cooperation scenarios to maximize cost efficiency
• Established Industrial/Scientific Network
  single-source repository for pharmaceutical engineering